This facility characterizes the size and size distribution of polymers and nano-objects. FFF technology in particular characterizes the size of all nanometric systems ranging from the macro-molecular scale (proteins, polysaccharides, micelles, polymers) to the particle (microparticles, nanoparticles, viruses, etc.).
Characteristics
- HPLC Shimadzu chain upstream coupled with Channel LC or Frit-inlet channel (Wyatt), membranes possible regenerated cellulose acetate 1, 5 or 10 kD or PES 5 or 10 kD
- Eclipse fractionation system of Wyatt (the different streams are adjusted according to the type of material to analyze)
- RI Sopares detector
- UV detector accordable in wavelength
- MALS Dawn Eleos Wyatt 18-angle detector
Applications
- RAMMI – use of polysaccharides coupled with innovative radioisotopes
- TheraneaM – use of microparticles as carriers of medicine for the processing of large tumors by radionuclide therapy
- Gadolymph project – use of nanohydrogels encapsulating gadolinium contrast agents for MRI
- AGuiX® project – use of nanoparticles for PET-MRI
Analysis better suited for materials under 1µm in size, only in an aqueous solution (no organic solvent).
| Identity | ||
| Equipment name | Asymmetric Flow Field Flow Fractionation | |
| Manufacturer | Wyatt | |
| Location | Arronax | |
| Name of the owner institution | Subatech – Arronax | |
| Type of equipment | Measurement of the size and size distribution of nanoparticles and polymers | |
| Fonctionnement | ||
| Availability of equipment | Available | |
| Equipment in controlled zone | Yes | |
| Restrictions of use | Users must be trained | |
| Technical correspondent | Contact us | |