publication 2014-1

Synthesis and Biological Properties of Quilamines II, New Iron Chelators with Antiproliferative Activities Corcé V.; Renaud S.; Cannie I.; Julienne K.; Gouin G.; Loréal O.; Gaboriau F.; Deniaud, D.Bioconjugate. Chem., 2014, 25 (2), 320-334.

To selectively target tumor cells expressing an overactive Polyamine Transport System (PTS), we designed, synthesized and evaluated the biological activity of a new generation of iron chelators, derived from the lead compound HQ1-44, which we named Quilamines II.