Publication 2014 -2

Synthesis and characterization of a stable copper(I) complex for radiopharmaceutical applications Bodio E.; Boujtita M.; Julienne K.; Le Saec P.; Gouin S.G.; Hamon J.; Renault E.; Deniaud D.ChemPlusChem, 2014, 79, 1284-1293.

N 4 Cu complexes: A series of ligands has been synthesized and their complexation with copper(II) precursors studied. The combination of several analytical techniques and density functional calculations shows that N 4  copper(I) complexes are formed from a copper(II) salt.Preliminary tests of complexation show the ability of these ligands to chelate 64 Cu in very diluted medium, which is of interest for developing new positron emission tomography imaging agents.